Kilic-Toprak, EmineUnver, FatmaErkek, Ozgen KilicKorkmaz, HaulOzdemir, YasinOymak, BurakOskay, Alten2024-06-132024-06-1320180006-355X1878-503410.3233/BIR-1801752-s2.0-85058594937https://doi.org/10.3233/BIR-180175https://hdl.handle.net/11501/1416BACKGROUND: Isokinetic exercise is used to reduce strength imbalance and to enhance performance. OBJECTIVE: The aim of this study was to investigate the acute effects of a single bout of eccentric isokinetic exercise on hemorheology (erythrocyte deformability and aggregation), total oxidant/antioxidant status (TOS/TAS) and oxidative stress index (OSI) in active individuals. METHODS: The study comprises 11 active, healthy, male subjects (mean age of 19.45 +/- 0.31 years, BMI 22.05 +/- 0.51 kg/m(2)). They performed single, unilateral eccentric contractions of knee flexors and extensors with dominant leg on a dynamometer. Isokinetic hamstring, quadriceps strength were recorded at eccentric (30, 120 degrees s(-1)) angular velocities. Eight active age-matched healthy male subjects were included as a control group, who did not receive exercise. Blood samples were obtained before, immediately after and two days after the exercise session. Hemorheological parameters were measured by an ektacytometer. TOS/TAS were determined using a commercial kit. RESULTS: A session of eccentric isokinetic exercise did not affect erythrocyte deformability and oxidative stress indices, whereas red blood cell (RBC) aggregation was increased initially and returned to pre-exercise levels after two days following exercise. CONCLUSION: Our results suggest that, increased RBC aggregation following an acute bout of isokinetic exercise may result in increased plasma skimming that augments tissue perfusion and clearance of metabolites within a period of two days following exercise.eninfo:eu-repo/semantics/closedAccessHemorheologyOxidative StressEccentric ExerciseRed Blood Cell AggregationOxidative StressMuscle StrengthBlood RheologyTime-CourseResistanceDamageYoungContractionParametersResponsesArticle24130530954Q31555WOS:000453889300002Q4