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Effect of telerehabilitation based high intensity interval training on biochemistry parameters and symptoms in patients with fibromyalgia
(Dokuz Eylül University, 2025) Akıl Ağdere, Selin; Pehlivan, Esra; Kat, Ezgi; Helvacı, Nazlı; Kural, Alev; Vural, Meltem
Purpose: The aim of this study was to evaluate the effect of telerehabilitation-based high intensity interval training (HIIT) on biochemistry parameters and disease symptoms in fibromyalgia patients. Fibromyalgia syndrome (FMS) is a chronic musculoskeletal disease of unknown etiology accompanied by symptoms such as pain, hyperalgesia, sleep disorders, fatigue and mood disorders. Material and Methods: 33 fibromyalgia patients were randomly assigned as HIIT (n = 11), moderate-intensity continuous training (MICT)(n = 11) and control group (CG)(n = 11). While the patients in the study groups were given upper extremity exercise with telerehabilitation for 6 weeks, no intervention was applied to the CG. Disease symptoms and blood parameters were evaluated before and after treatment. Results: After the treatment, significant changes were found in the results of superoxide dismutase (SOD), malondialdehyde (MDA), glutathione peroxidase GSH(Px), right hand grip strength, pressure pain threshold, fatigue severity and disability in the HIIT group, and in the results of SOD, myeloperoxidase (MPO), left hand grip strength and fatigue severity in the MICT group (p<0.05).