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  • Küçük Resim Yok
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    Antibacterial Characteristics of Nanofiber Structures Obtained by Benzalkonium Chloride Additive Poly (Vinyl Alcohol)/Gelatin
    (2019) Yolay, Onur; Yüksek, Metin; Tezcan, Erdem; İşgören, Erkan; Saltık, Derya
    Polyvinyl alcohol (PVA) is a hydrophilous and semi-crystallized. It has attracted much relevancy due to its pretty chemical endurance, finethermal determination, decent physical specialities, wonderful bio-compatibility and cheapness. Gelatin (G) is a natural polymer and thatare interesting materials for biomedical applications. Electrospinning is a simple method that provides very porous nanofiber productionwith high surface area. It is possible to produce biomedical, filtration, energy storage and protective materials by using electrospinningmethod. Benzalkonium chloride (BAC) is a kind of anti-microbial cationic surface-active agent, which has been pretty used in merchantwound dressings and has a powerful status toward Gr+ bacteria.In this study, nanofibers were produced from electrospinning of BAC, PVA and G containing solutions at various concentrations. The fibersof obtained nanofiber structure were uniform, continuous and intensive. The optimum parameters in terms of good mechanical and antibacterialproperties were determined. S2 sample, electrospun from 11.63% PVA + 1.0% G +1.0% BAC containing solution, had the bestmorphological and mechanical properties due to having the thinnest fiber diameter (51±13nm) and the highest vertical strength (4.299MPa)and horizontal strength (4.058MPa). It also had antibacterial activity against all the bacteria tested (E. coli, P. aeruginosa, B. subtilis andS. aureus). Due to owning good mechanical and antibacterial properties, S2 sample can have many uses in medical sector.
  • Küçük Resim Yok
    Öğe
    Application for dissolution of coronary atherosclerotic plaque: a new treatment?
    (Elsevier Ireland Ltd, 2023) Yolay, Onur; Kasapbaşı, Esat; Öztürk, Volkan; Tezcan, Erdem; Karaoğlu, Hülya; Küçük, C.; Hazıroğlu, Ceyhun; Olcay, Ayça
    [Abstract Not Available]