Synthesis, Characterization and absorption properties of some novel heterocyclic tetrakisazo dyes
Küçük Resim Yok
Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
International Journal of Pharmacy and Pharmaceutical Science
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: The aim of the work was to designed and synthesized novel heterocyclic tetrakisazo dyes.Methods: 2,2'[(4,4'-dihydrazonebiphenyl)]-bis(3-iminobuthyronitrile) (1) were synthesized by diazotization of benzidine using hydrochloric acid in water. Compounds (1) reacted with hydrazine hydrate to afford the corresponding 4,4'-bis [3-methyl-5-amino-1-H-pyrazol-4-ylazo]biphenyl (2). Seven novel hetaryltetrakisazobenzidine Derivatives 3(a-g) were achieved by diazotization of 4,4'-bis [3-methyl-5-amino-1-H-pyrazol-4-ylazo]biphenyl and coupling with various coupling components.Results: The obtained hetaryltetrakisazo dyes 3(a-g) were characterized based on FT-IR, 1H-NMR, and mass spectroscopic techniques as well as elemental analysis. The solvatochromic behavior of these dyes in various solvents was examined. Acid-base effects on the visible absorption maxima of the dyes were also reported.Conclusion: Synthesis and characterization of seven of these nine novel compounds synthesized, which are hetaryltetrakisazo dyes 3(a-g). © 2014,International Journal of Pharmacy and Pharmaceutical Sciences All Rights Reserved.
Açıklama
Anahtar Kelimeler
Diazo-coupling reaction, Diazotization, Pyrazole, Solvatochromism, Tetrakisazo dyes, 4,4' bis [(2',4' dihyroxyquinoline 3') ylazo1 h pyrazole 4 ylazo] biphenyl, 4,4' bis [3 methyl 5 (2' hydroxynaphthaline 1' ylazo) 1 h pyrazole 4 ylazo] biphenyl, 4,4' bis [3 methyl 5 (2' hydroxypyridine 3' ylazo) 1 h pyrazole 4 ylazo] biphenyl, 4,4' bis [3 methyl 5 (3' methyl 5' hydroxy 1' h pyrazole 4' ylazo) 1 h pyrazole 4 ylazo] biphenyl, 4,4' bis [3 methyl 5 (4' hydroxy 6' methyl 2' pyrone 3' ylazo) 1 h pyrazole 4 ylazo] biphenyl, 4,4' bis [3 methyl 5 (4' hydroxycoumarine 3' ylazo) 1 h pyrazole 4 ylazo] biphenyl, 4,4' bis [3 methyl 5 (8' hydroxyquinoline 7' ylazo) 1 h pyrazole 4 ylazo] biphenyl, azo compound, hetaryltetrakisazobenzidine derivative, unclassified drug, absorption, Article, diazotization, drug synthesis, infrared spectroscopy, mass spectrometry, proton nuclear magnetic resonance, solvent effect, thin layer chromatography, ultraviolet spectrophotometry
Kaynak
International Journal of Pharmacy and Pharmaceutical Sciences
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
6
Sayı
9