Synthesis, Characterization and absorption properties of some novel heterocyclic tetrakisazo dyes

Küçük Resim Yok

Tarih

2014

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

International Journal of Pharmacy and Pharmaceutical Science

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Objective: The aim of the work was to designed and synthesized novel heterocyclic tetrakisazo dyes.Methods: 2,2'[(4,4'-dihydrazonebiphenyl)]-bis(3-iminobuthyronitrile) (1) were synthesized by diazotization of benzidine using hydrochloric acid in water. Compounds (1) reacted with hydrazine hydrate to afford the corresponding 4,4'-bis [3-methyl-5-amino-1-H-pyrazol-4-ylazo]biphenyl (2). Seven novel hetaryltetrakisazobenzidine Derivatives 3(a-g) were achieved by diazotization of 4,4'-bis [3-methyl-5-amino-1-H-pyrazol-4-ylazo]biphenyl and coupling with various coupling components.Results: The obtained hetaryltetrakisazo dyes 3(a-g) were characterized based on FT-IR, 1H-NMR, and mass spectroscopic techniques as well as elemental analysis. The solvatochromic behavior of these dyes in various solvents was examined. Acid-base effects on the visible absorption maxima of the dyes were also reported.Conclusion: Synthesis and characterization of seven of these nine novel compounds synthesized, which are hetaryltetrakisazo dyes 3(a-g). © 2014,International Journal of Pharmacy and Pharmaceutical Sciences All Rights Reserved.

Açıklama

Anahtar Kelimeler

Diazo-coupling reaction, Diazotization, Pyrazole, Solvatochromism, Tetrakisazo dyes, 4,4' bis [(2',4' dihyroxyquinoline 3') ylazo1 h pyrazole 4 ylazo] biphenyl, 4,4' bis [3 methyl 5 (2' hydroxynaphthaline 1' ylazo) 1 h pyrazole 4 ylazo] biphenyl, 4,4' bis [3 methyl 5 (2' hydroxypyridine 3' ylazo) 1 h pyrazole 4 ylazo] biphenyl, 4,4' bis [3 methyl 5 (3' methyl 5' hydroxy 1' h pyrazole 4' ylazo) 1 h pyrazole 4 ylazo] biphenyl, 4,4' bis [3 methyl 5 (4' hydroxy 6' methyl 2' pyrone 3' ylazo) 1 h pyrazole 4 ylazo] biphenyl, 4,4' bis [3 methyl 5 (4' hydroxycoumarine 3' ylazo) 1 h pyrazole 4 ylazo] biphenyl, 4,4' bis [3 methyl 5 (8' hydroxyquinoline 7' ylazo) 1 h pyrazole 4 ylazo] biphenyl, azo compound, hetaryltetrakisazobenzidine derivative, unclassified drug, absorption, Article, diazotization, drug synthesis, infrared spectroscopy, mass spectrometry, proton nuclear magnetic resonance, solvent effect, thin layer chromatography, ultraviolet spectrophotometry

Kaynak

International Journal of Pharmacy and Pharmaceutical Sciences

WoS Q Değeri

Scopus Q Değeri

N/A

Cilt

6

Sayı

9

Künye