Ti6Al4V 3D-printed lattice structures for biomedical applications

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dc.contributor.authorGürkan, Doruk
dc.contributor.authorSağbaş, Binnur
dc.date.accessioned2025-10-30T10:23:25Z
dc.date.available2025-10-30T10:23:25Z
dc.date.issued2025
dc.departmentFakülteler, Mühendislik Fakültesi, Makine Mühendisliği Bölümü
dc.description.abstractTi6Al4V alloy is widely recognized in the biomedical field, particularly for orthopedic and dental implants, due to its excellent biocompatibility, high specific strength, and exceptional corrosion resistance. The advent of 3D printing technologies has made it possible to fabricate complex lattice structures with controlled porosity and geometry. These structures are highly advantageous in biomedical applications as they can mimic the trabecular architecture of bone, improving osseointegration and enhancing the performance of implants in load-bearing environments. A key challenge with traditional solid implants is the phenomenon of stress shielding, where the stiffness of the implant exceeds that of the surrounding bone, leading to a reduction in the bone’s natural load-bearing function. This can result in bone resorption and implant loosening over time. To address this issue, 3D-printed Ti6Al4V lattice structures are designed to reduce stiffness and more closely match the mechanical properties of human bone, thereby minimizing stress shielding effects. Although mechanical performance is critical, the biocompatibility of these structures is also essential. In vitro studies, including cell adhesion, proliferation, and differentiation tests, have been used to assess the interaction of these materials with osteoblast-like cells. Surface roughness and residual stress are identified as challenges that can affect both mechanical and biological performance. Post-processing techniques such as heat treatment and surface polishing are analyzed for their effectiveness in addressing these issues. In this chapter, various lattice geometries and their mechanical performance, focusing on optimizing parameters such as elastic modulus, yield strength, and fatigue resistance, will be discussed. Additionally, the influence of key 3D printing parameters, including laser power, scan speed, and layer thickness, on the mechanical and microstructural properties of the lattice structures will be discussed. The role of porosity in promoting bone ingrowth and vascularization is also highlighted, emphasizing the balance between mechanical integrity and biological functionality. 3D-printed Ti6Al4V lattice structures hold great promise for improving the performance and longevity of biomedical implants by offering a customizable approach tailored to patient-specific needs. By mitigating stress shielding and enhancing bone-implant integration, these advanced structures are paving the way for the next generation of high-performance biomaterials for clinical use. Furthermore, the sustainability aspects of 3D printing, including reduced material waste, energy efficiency, and longer-lasting implants, are key benefits in advancing the field of sustainable biomedical applications.
dc.identifier.doi10.1201/9781003557715-16
dc.identifier.endpage406
dc.identifier.isbn9781040427491
dc.identifier.isbn9781032902203
dc.identifier.scopus2-s2.0-105019147349
dc.identifier.scopusqualityN/A
dc.identifier.startpage359
dc.identifier.urihttps://doi.org/10.1201/9781003557715-16
dc.identifier.urihttps://hdl.handle.net/11501/2498
dc.indekslendigikaynakScopus
dc.institutionauthorGürkan, Doruk
dc.institutionauthorid0000-0001-8507-8592
dc.language.isoen
dc.publisherCRC Press
dc.relation.ispartofAdvanced Technologies for Sustainable Biomedical Applications
dc.relation.publicationcategoryKitap Bölümü - Uluslararası
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAluminum Alloys
dc.subjectBearings (Machine Parts)
dc.subjectBiocompatibility
dc.subjectBiological Implants
dc.subjectBiomechanics
dc.subjectBone
dc.subjectCell Adhesion
dc.subjectCorrosion Resistance
dc.subjectDental Prostheses
dc.subjectElastic Moduli
dc.titleTi6Al4V 3D-printed lattice structures for biomedical applications
dc.typeBook Chapter

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