COVID-19 enfektivitesi ve fatalitesi üzerine bir değerlendirme: meta-analiz çalışması
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Dosyalar
Tarih
2023
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Yayıncı
Galenos Yayınevi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Kanıta dayalı çalışmalar arasında en yüksek seviyede yer alan meta analiz yöntemi kullanılarak yürütülen bu çalışma, tüm dünyayı sarsan Koronavirüs hastalığı-2019 (COVID-19) virüsünün enfektivitesi ve fatalitesinin etki büyüklüğünü incelemektir. Gereç ve Yöntem: COVID-19’un dünyada ilk görüldüğü tarih olarak ifade edilen Aralık 2019 ile Aralık 2020 zaman dilimleri arasında yapılan kapsamlı bir literatür taraması (PubMed, Medline, Cochrane Library, Science Direct, ProQuest, Ulakbim, Sağlık Bakanlığı, YÖK, WHO Global İndex) gerçekleştirildi. Çalışma için seçme kriterleri belirlendi. Çalışmaya seçme kriterlerine uyan 21 çalışma dahil edildi. Araştırmada analiz edilen makaleler, birbirinden bağımsız iki kodlayıcı tarafından kodlanarak, araştırmaya dahil edilecek çalışmaların metodolojik kalitesi “Jadad skoru” ve “Newcastle Ottawa Ölçütü” kullanılarak değerlendirildi. Araştırmaya orta ve yüksek kalitedeki çalışmalar dahil edildi. Verileri analiz etmek için Comprehensive Meta Analysis programının üç sürümü kullanıldı. Bulgular: COVID-19 enfektivite ve fatalitesi üzerine yapılan çalışmamızın etki büyüklüğü d=0,092 (p=0,000) olarak hesaplandı. Cohen’e (1988) göre araştırmalar yüksek etki büyüklüğüne sahip ve heterojen yapıda bulundu. Heterojeniteyi araştırmak için yapılan alt grup verilerine ait moderatör analizi sonucuna göre, yaş, cinsiyet, klinik bulgu ve komorbiditenin ortalama etki büyüklüğü için bir moderatör olduğu (p<0,05) saptandı. Bu bağlamda COVID-19 enfektivite ve fatalitesinin demografik özellikler, klinik tablo ve komorbidite ile anlamlı ve etkili olduğu saptandı. Sonuç: Pandemi gibi global halk sağlığı sorunlarında hemşirelik alanında meta-analiz yöntemi kullanılarak yapılan ve pandeminin ilk yılını kapsayan bir çalışma olması nedeniyle, daha geniş bir zaman dilimi kullanılarak, geniş yaş kategorilerinde ve daha farklı ülkelerde yapılan çalışmaların da eklenmesiyle yapılacak çalışmalar için yol gösterici olacağı düşünülmektedir.
Aim: The effect size of the infectivity and fatality of the Coronavirus disease -2019 (COVID-19) virus, which shook the whole world, was examined using the meta -analysis method, which is considered to have high evidential value. Materials and Methods: A comprehensive literature review (PubMed, Medline, Cochrane Library, Science Direct, ProQuest, Ulakbim, Ministry of Health, YoK, WHO Global Index) was conducted between December 2019, the date of COVID-19 virus's first appearance in the world, and December 2020. Selection criteria for the study were determined. Twenty-one studies that met the criteria were included. The analyzed articles were coded by two independent coders, and the methodological quality of the studies to be included in the research was evaluated using the Jadad score and the Newcastle Ottawa Criterion. Studies of medium and high quality were included in the study. Three versions of the Comprehensive Meta -Analysis program were used to analyze the data. Results: The effect size on COVID-19 transmission and mortality was calculated as d=0.092 (p=0.000). According to Cohen (1988), studies have high effect sizes and are heterogeneous. According to the results of the moderator analysis investigating the heterogeneity of subgroup data, age, gender, clinical findings and comorbidity were found to be moderators for the mean effect size (p<0.05). In this context, demographic characteristics, clinical picture and comorbidity, as well as COVID-19 transmissibility and mortality rate, were determined to be significant and effective. Conclusion: Due to the fact that it is a study covering the first year of the pandemic using the meta -analysis method in the field of nursing in global public health problems such as pandemics, it is thought that it will guide the studies to be done by using a wider time period and adding studies conducted in wider age categories and in different countries.
Aim: The effect size of the infectivity and fatality of the Coronavirus disease -2019 (COVID-19) virus, which shook the whole world, was examined using the meta -analysis method, which is considered to have high evidential value. Materials and Methods: A comprehensive literature review (PubMed, Medline, Cochrane Library, Science Direct, ProQuest, Ulakbim, Ministry of Health, YoK, WHO Global Index) was conducted between December 2019, the date of COVID-19 virus's first appearance in the world, and December 2020. Selection criteria for the study were determined. Twenty-one studies that met the criteria were included. The analyzed articles were coded by two independent coders, and the methodological quality of the studies to be included in the research was evaluated using the Jadad score and the Newcastle Ottawa Criterion. Studies of medium and high quality were included in the study. Three versions of the Comprehensive Meta -Analysis program were used to analyze the data. Results: The effect size on COVID-19 transmission and mortality was calculated as d=0.092 (p=0.000). According to Cohen (1988), studies have high effect sizes and are heterogeneous. According to the results of the moderator analysis investigating the heterogeneity of subgroup data, age, gender, clinical findings and comorbidity were found to be moderators for the mean effect size (p<0.05). In this context, demographic characteristics, clinical picture and comorbidity, as well as COVID-19 transmissibility and mortality rate, were determined to be significant and effective. Conclusion: Due to the fact that it is a study covering the first year of the pandemic using the meta -analysis method in the field of nursing in global public health problems such as pandemics, it is thought that it will guide the studies to be done by using a wider time period and adding studies conducted in wider age categories and in different countries.
Açıklama
Anahtar Kelimeler
COVID-19, Enfektivite, Fatalite, Koronavirüs, Meta-Analiz, COVID-19, Infectivity, Fatality, Coronavirus, Meta-Analysis
Kaynak
Namık Kemal Tıp Dergisi
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
11
Sayı
4
