Sleeve gastrectomy versus Roux-en-Y-gastric bypass in patients with body mass index over 50 kg/m2: international multicentre cohort
| dc.contributor.author | Kollmann, Lars | |
| dc.contributor.author | Rosenblum, Ilan | |
| dc.contributor.author | Poljo, Adisa | |
| dc.contributor.author | Probst, Pascal | |
| dc.contributor.author | Muller, Markus K. | |
| dc.contributor.author | Kalinowski, Piotr | |
| dc.contributor.author | Dalkılıç, Muhammed S. | |
| dc.contributor.author | Şişik, Abdullah | |
| dc.date.accessioned | 2026-05-08T13:44:55Z | |
| dc.date.available | 2026-05-08T13:44:55Z | |
| dc.date.issued | 2026 | |
| dc.department | Meslek Yüksekokulu, Gedik Meslek Yüksekokulu, Anestezi Programı | |
| dc.description.abstract | Background Patients with initial body mass index > 50 kg/m(2) are vastly under-represented in randomized clinical trials demonstrating similar weight loss and diabetes remission rates after sleeve gastrectomy and Roux-en-Y gastric bypass. Methods Propensity score matching 1 : 1 was used to compare outcomes regarding weight loss and diabetes control after sleeve gastrectomy and Roux-en-Y gastric bypass in patients with body mass index > 50 kg/m(2) between 2012 and 2022 in a cohort from 13 centres in six European countries. The primary endpoint was percentage total bodyweight loss; secondary endpoints were diabetes remission rate and rate of persistent body mass index > 40 kg/m(2). Results In total, 3976 of 8160 patients were matched and included in the analysis (1988 in each group). Median age at baseline was 40.0 (range 16-76) years in the sleeve gastrectomy group and 39.5 (15-71) years in the Roux-en-Y gastric bypass group. Median body mass index at baseline was 56.2 (range 50.0-100.0) and 54.3 (50.0-83.9) kg/m(2), respectively (P < 0.001). The follow-up rate was 70.5% at 1 year and 24.4% at 5 years. Percentage total bodyweight loss at 1 and 5 years after sleeve gastrectomy was 30.2 (2.2-63.7) and 25.4 (-4.8 to 56.0)%, respectively, versus 31.2 (7.4-54.5) and 28.2 (-6.6 to 62.9)% in the Roux-en-Y gastric bypass group (P < 0.001 between groups in both time points). The prevalence of persistent body mass index > 40 kg/m(2) after 1 and 5 years was 42.7 and 57.6%, respectively, after sleeve gastrectomy versus 24.5 and 39.2% after Roux-en-Y gastric bypass (P < 0.001 between groups in both time points). A 5-year follow-up, the prevalence of a pathological haemoglobin A1c level (> 6.5%) was 12.9% after sleeve gastrectomy and 11.6% after Roux-en-Y gastric bypass (P = 0.323). Conclusion This study suggests that Roux-en-Y gastric bypass results in greater weight loss than sleeve gastrectomy in patients with body mass index > 50 kg/m(2), whereas improvements in diabetes appear comparable between procedures. | |
| dc.identifier.doi | 10.1093/bjsopen/zrag028 | |
| dc.identifier.issn | 2474-9842 | |
| dc.identifier.issue | 2 | |
| dc.identifier.pmid | 42053467 | |
| dc.identifier.scopus | 2-s2.0-105037425998 | |
| dc.identifier.scopusquality | Q1 | |
| dc.identifier.uri | https://doi.org/10.1093/bjsopen/zrag028 | |
| dc.identifier.uri | https://hdl.handle.net/11501/2700 | |
| dc.identifier.volume | 10 | |
| dc.identifier.wos | WOS:001753186300001 | |
| dc.identifier.wosquality | Q1 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | PubMed | |
| dc.indekslendigikaynak | Scopus | |
| dc.institutionauthor | Şişik, Abdullah | |
| dc.institutionauthorid | 0000-0002-7500-8651 | |
| dc.language.iso | en | |
| dc.publisher | Oxford University Press | |
| dc.relation.ispartof | BJS Open | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Weight Loss | |
| dc.subject | Diabetes Remission | |
| dc.subject | Obesity Class IV | |
| dc.title | Sleeve gastrectomy versus Roux-en-Y-gastric bypass in patients with body mass index over 50 kg/m2: international multicentre cohort | |
| dc.type | Article |
